ESR1 and neoplasm: It can be seen that the prediction score appears to be a more accurate predictor (AUC 0.81, 95% CI 0.6–1.0) than the combination of clinical covariates ER H score and tumor grade (AUC 0.74, 95% CI 0.47–1.0), but the combination of prediction score and covariates is superior (AUC 0.91, 95% CI 0.73–1.0).