Although the rearrangement hotspot and gene fusions identified in our studies are different, the presence of a pseudogene with homology to a RAS related leukemia viral oncogene within the identified hotspot is suggestive that perhaps gene fusions involving NAV3-SYT1-PAWR may also play a yet unidentified role in other cancers in addition to well-differentiated liposarcoma. Here, NAV3 is linked to liposarcoma.