It is noteworthy that among proteins identified by single peptide hits (Supplementary Table S1), several proteins of analogous function to the above, such as glutathione S-transferase isoform-1, Cu-Zn superoxide dismutase, were also depleted indicating that possibly a broader range of resident BAL proteins are depleted during acute and inflammatory stages of influenza infection. The gene discussed is SOD1; the disease is influenza.