KRAS and pancreatic intraductal papillary-mucinous neoplasm: In the three remaining cases (#31, #44 and #46, Table 4) a mutation in KRAS exon 3 was detected only using 454-NGS and all three cases were IPMN (two BD-IPMN and one MD-IPMN) after post-operative histologic evaluation (Figures 2 A–C).