BRCA1 and ovarian carcinoma: A number of specific genes have been identified as playing a role in ovarian carcinogenesis; the ones that have received the most attention are BRCA1 and BRCA2 followed by TP53. In addition, integrated genomic analysis of ovarian carcinomas has identified four ovarian cancer transcriptional subtypes, three microRNA subtypes, four promoter methylation subtypes, and a transcriptional signature associated with survival duration [2], attesting to the genetic complexity of these tumors.