To understand whether PTH may show a direct neuroprotective effect when administrated via a systemic injection, we measured infarct formation 3 days after the onset of MCA occlusion in mice that received saline (n = 9) and PTH treatment (80 μg/kg, i.p. 1 hr after stroke and ×3 days, n = 10). This evidence concerns the gene PTH and Stroke.