LGALS1 and cancer: Processing of the LM-γ2 chain to the mature form decreases cell adhesion activity but increases cell migration and invasion activity of LM-5 in human cancer cells.44 These results suggest that the Gal-1-induced LM-γ2 may contain a functional domain that regulates cellular adhesion and migration as well as Gal-1-mediated induction of LM-5.