By virtue of its pathology, it is not surprising that PSP risk has been consistently associated with the H1 haplotype of the tau gene (MAPT) (Baker et al., 1999; Conrad et al., 1997; Ezquerra et al., 1999) (for review, see Vandrovcova et al., 2010). This evidence concerns the gene MAPT and supranuclear palsy, progressive, 1.