PSP is a primary tauopathy with widespread tau pathology mainly defined by hyperphosphorylated tau protein, neurofibrillary tangles, neuropil threads and characteristic glial tau inclusions, astrocytic tufts, and oligodendroglial-coiled bodies in the white matter (Dickson et al., 2007). This evidence concerns the gene MAPT and supranuclear palsy, progressive, 1.