In agreement with their role in stellate cell proliferation, nuclear FGF2 and FGFR1 were associated with Ki67 positivity in PS1 cells (Supplementary Fig 7A–C), however no effect was seen in cancer cells upon FGF2 or FGFR1 knockdown (Supplementary Fig 4C and 8A–F). This evidence concerns the gene FGFR1 and cancer.