Asthmatic individuals showed an increase in ECP (Median 286 pg/ml to 507 pg/ml after viral infection, p = 0,04) and IL-8 (Median 0.34 pg/ml to 1.42 pg/ml after viral infection, p = 0,04) in BALF after rhinovirus exposure [21]. This evidence concerns the gene RNASE3 and viral infectious disease.