Multinomial logistic regression analysis revealed that prevalence odds for all four conditions (DM, DM + CAD 5Y, DM + CAD 10y and CAD) are higher in those with high cyclophilin values, compared to those with lower values, after adjusting for age and sex, indicating strong association of high cyclophilin values with diabetes and vascular disease. The gene discussed is PPIB; the disease is coronary artery disorder.