Since no studies have examined the expression levels of DNA-repair proteins (MGMT, ERCC1, hMSH2, and hMLH1) in pancreatic cancer induced by DMBA and non-cancerous pancreatic cancer tissues in rats, little is known about the effects of MGMT, ERCC1, hMSH2, and hMLH1 on rat pancreatic cancer induced by DMBA. Here, MLH1 is linked to pancreatic neoplasm.