CFTR and nutritional deficiency disease: Moreover, the changes in a pup’s body weight evolution and length of the CF and TF groups compared to the C and T groups (Figure 1) accompanied by a reduction in the liver relative weight of the TF group compared to the T group (Table 2) are consistent with the hypothesis that the 10% oligofructose supplementation during pregnancy and lactation contributes to offspring malnutrition, most likely as a consequence of impaired somatic and morphologic development.