Gene copy number of INPP4B, expression of INPP4B, pAkt, PDPK1 and PTEN, mutations of PIK3CA,PTEN, KRAS, BRAF as well as IRS-1 G972R genotypes in relation to NSCLC subtype (ADCA and SCC) and gender. The gene discussed is PIK3CA; the disease is non-small cell lung carcinoma.