ERBB2 and breast carcinoma: A molecular classification based on a clustering analysis of the expression patterns of 427 genes has divided breast cancer into four types: a luminal type (further divided into A, B and C subtypes), a basal-like type, a Her-2 positive type, and a normal breast-like type [57,58], and the molecular classifications are closely correlated with the prognoses, with the luminal subtype A having a good clinical outcome; the luminal subtype B having a bad prognosis; and the basal-like and the Her-2 positive types having the worst clinical outcome [58].