NMBAs-induced anaphylaxis is a rare intraanesthetic event having an estimated incidence of 250.9/ 1 million anaesthetics, with life-threatening clinical symptoms like hypotension, shock or cardiac arrest in 36.39% cases of non-IgE-mediated reactions and 84.04% IgE-mediated allergic reactions[3]. Here, IGHE is linked to anaphylaxis.