Indeed, these results indicate that: IL6 pathways are involved in Treg cell imbalance and produce a worsening of the neurological deficit in both men and women groups of multiple sclerosis patients, but the efficacy of IFNy-treatment in the re-establishment of The cell network balance (the immune response homeostasis) and delaying the progression of neurological disability (the neurological response homeostasis) is linked to the re-establishment of IL6 pathway in women and of IFNγ pathway in men [55]. The gene discussed is IL6; the disease is multiple sclerosis.