Specifically, Berardinelli–Seip congenital lipodystrophy is a condition associating insulin resistance, absence of subcutaneous fat, AN, and muscular hypertrophy caused by mutation in either AGPAT2 (OMIM#603100) or BSCL2 (OMIM# 606158) (Friguls et al. This evidence concerns the gene AGPAT2 and Insulin resistance.