Mutations in SLC4A4 have been reported in pedigrees with proximal renal tubular acidosis (pRTA) with HM and migraine (Demirci et al. 2006; Suzuki et al. 2010), but this gene was not considered in this study as none of the patients in our series showed renal abnormalities. The gene discussed is SLC4A4; the disease is migraine disorder.