There was also a considerable increase in the expression of others genes described as stem cell markers and expressed in CD44high fractions of normal and breast cancer tissues [36], including FOXC1(∼11-fold), IGFBP7 (∼8.5-fold), PROCR (∼8.2-fold), LEF1 (∼6.7-fold) and ZEB1 (∼6.6-fold). This evidence concerns the gene LEF1 and breast cancer.