Some HLA-DRB1 alleles are reported to be positively associated with SLE susceptibility in several ethnic groups studied: DRB1*03:01 and *15:01 in European [7], [8], *15:03 in African-American [9], *08:02 in Hispanic [10] and *15:01 and *15:02 in Asian populations [11], [12], [13], [14]. This evidence concerns the gene HLA-DRB1 and systemic lupus erythematosus.