Further rounds after elimination of DRB1*15:01, *13:02 or *14:03 carriers revealed only tendential associations between the remaining DRB1 alleles and SLE, particularly for DRB1*04:06 (P = 0.0020, Pc = 0.0509), *08:02 (P = 0.0082, Pc = 0.2040), *08:03 (P = 0.0151, Pc = 0.3615) and *04:03 (P = 0.0117, Pc = 0.2683). This evidence concerns the gene HLA-DRB1 and systemic lupus erythematosus.