PRODH and schizophrenia: In the comparison of all PRODH genotypes with all brain volumes and cortical thicknesses, only one association remained significant after Bonferroni correction: the interaction between rs2238731 (V427M) and schizophrenia was associated with right pars opercularis volume (p  = 0.00020; effect size  = 0.081; power  = 0.965).