Masumoto reported that a monoclonal antibody against ITGB1 blocked HCC cell invasion [35], and Mizuno found that overexpression of α3β1 integrins enhanced HepG2 cell migration and invasion [36], while inhibition of α3β1 integrins suppressed SMMC-7721 cell migration [37]. The gene discussed is ITGB1; the disease is hepatocellular carcinoma.