We have found a Meis1 binding peak 27 kb upstream of Hif1a exon 1 by Chip-seq analyses and a reduction in its expression by conditional deletion of Meis1 in AML cells (T. N., unpublished data), although another study did not show such a binding peak within the Hif1a locus [37]. This evidence concerns the gene HIF1A and acute myeloid leukemia.