PNPLA3 and steatosis: In the entire cohort, multivariate logistic regression analysis showed that high BMI (OR 1.10, 95% CI 1.04–1.117, p = 0.001), high HOMA considered as continuous variable (OR 1.08, 95% CI 1.00–1.17, p = 0.04), and PNPLA3 GG (OR 1.97, 95% CI 1.11–3.51, p = 0.02) were independently associated with severe steatosis (table 3 upper panel).