INS and Hyperglycemia: GLU-rats showed a significant increase in blood glucose (18±4.0 mmol/L) and insulin (11.0±1.5 mmol/L) levels compared with control rats (6.3±1.1 mmol/L, 0.57±0.50 mmol/L) (Figure 1A), implying that the GLU-rats exhibited hyperglycemia with a high insulin level.