At week 6, each of the rabbits in groups A was challenged with 2.5×106 copies of a rabbit HEV strain and those in group B with the same dose of a swine HEV strain of genotype 4.The course of the infection was monitored for 10 weeks after challenge by measuring serum ALT levels, viremia, fecal shedding and HEV antibody responses. Here, GPT is linked to infection.