Further analysis indicated that intratumoral GATA2 remained to be an independent predictor of tumor recurrence and patient death in subgroups of patients receiving prophylactic therapy (p = 0.039 for TTR and p = 0.005 for OS) or not (p = 0.003 for TTR and p = 0.027 for OS, Supplementary Fig. S3). The gene discussed is TTR; the disease is neoplasm.