In COPD patients, there was a significant negative correlation between the number of CD163+, CD204+ or CD206+ cells and %FEV1.0, but not the FEV1.0/FVC% ratio (r = 0.729, r = 0.739, r = 0.732, r = 0.765; Fig. 6). The gene discussed is CD163; the disease is chronic obstructive pulmonary disease.