A recent genome wide association study (GWAS) in a Korean SSc cohort revealed that the specific single nucleotide polymorphisms (SNPs) of human leukocyte antigen (HLA) DPB1 conferred the strongest susceptibility to SSc, and HLA-DPB1*13:01 and DPB1*09:01 were the most susceptible alleles to Korean SSc [6]. The gene discussed is HLA-DPB1; the disease is systemic sclerosis.