U2AF1 and lung adenocarcinoma: Moreover, we do not see this consensus 3′ splice site sequence in RBM10 LOF-associated splicing in lung adenocarcinoma (Figure S4A–B in Document S1) nor in splicing changes in HeLa cells transduced with wild-type U2AF1 (Figure S5C–D in Document S1), supporting that the sequence preference is specific to U2AF1 S34F/Y mutations.