On the contrary, when another HER2-positive breast tumor (case 601) described in [26] was tested, with the help of GIANT we found that HER2 was amplified not only in tumor but also in normal stroma (Figure 5), indicating that the stroma sample may actually be contaminated by the tumor cells due to imperfect microdissection. The gene discussed is ERBB2; the disease is breast neoplasm.