Moreover, Niewidok et al. (2012) have shown that the lung carcinoma cell line A549 possessing wt p53 and wt PTEN was much more sensitive to the Hsp90 inhibitor NVP-AUY922 [67] than was the SNB19 cell line which is mutated in both p53 and PTEN. This evidence concerns the gene PTEN and lung carcinoma.