COL8A1 and age-related macular degeneration: Since 2011, associations with AMD have been shown for a novel rare variant (R1210C) in CFH [3] common variants in COL10A1[4]–[6], COL8A1[4]–[6], VEGFA [5], and TNFRSF10A [6], [7] Additional common variants were also identified in our international consortium effort based on meta-analyses of several genome-wide case-control association studies.