AFP and Cirrhosis: Unfortunately, the relation between pre-treatment serum AFP-L3% levels and tumor invasion, metastasis and other clinicopathological parameters (such as tumor grade, stage, and cirrhosis) reported in those studies were not reliable, so we failed to estimate the association between pre-treatment serum AFP-L3% and those factors and can not determine the influence of these factors related to AFP-L3 level and OS or DFS.