AFP and hepatocellular carcinoma: Subgroup analysis indicated that high pre-treatment AFP-L3% levels were significantly related to DFS in HCC treated by surgical resection (HR: 2.02, 95% CI: 1.37–2.99, p = 0.0004), without significant heterogeneity in the data (x2 = 2.87, I2 = 30%, p = 0.24).