CD4 and AIDS: However, patients who developed non-AIDS events were significantly older compared to controls (46 years vs. 41, P<0.0001) and showed significantly longer cumulative ART exposure (9.7 years vs. 3.9, P<0.0001), lower CD4 nadir (124 cells/μL vs. 219, P<0.0001) and lower CD4+ T-cell count (371 cells/μL vs. 536, P = 0.005).