MRTFA and cancer: Finally, the genes of the SRF-independent/SAP-dependent group were associated with extremely high significance with cell cycle and cancer (-logP ≥ 25 and ≥ 30, respectively), while the SRF/Mkl1 target genes were associated with the same two categories at low significance only (-logP ≥ 2 and ≥ 7, respectively).