The difference in the frequencies for RA patients compared with controls was found to be significant for both survivin and Flt3L (P < 0.0001, Pearson chi-square) with an OR of 12.1 (95% CI = 5.3 to 27.6) and 11.0 (95% CI = 3.9 to 30.9), respectively, for predicting disease. The gene discussed is FLT3LG; the disease is rheumatoid arthritis.