In the Danish cohort of dementia cases, which included the C9ORF72-related CBS case, C9ORF72 expansions were also found in one patient clinically diagnosed with olivopontocerebellar degeneration (OPCD) (where his father had ALS) and one patient with atypical Parkinsonian syndrome (APS) [48]. Here, CBS is linked to amyotrophic lateral sclerosis.