However, among SLE patients with pulmonary fibrosis IL-8 concentration in BALF was significantly higher, FEV1 and FVC were significantly lower in patients with immunosuppressive treatment when compared with patients without immunosuppressive treatment (81.38 ± 81.23 vs. 29.61 ± 19.14, p < 0.05; 73.37 ± 18.67 vs. 101.75 ± 12.03, p < 0.01; 78.71 ± 23.76 vs. 106.00 ± 11.25, p < 0.05, respectively; Fig. 2; Table 7). Here, CXCL8 is linked to pulmonary fibrosis.