MTHFR and gastric adenocarcinoma: This is in contrast to patients with adenocarcinoma of the stomach: according to the old classification (gastric cancer including AEG II, III, UICC 6th) (Figures 2 and 3) as well as in gastric cancer according to the new classification (gastric cancer without AEG II, III, UICC 7th) the MTHFR A1298C polymorphism was a prognostic factor (p = 0.005 and 0.009 respectively), (Figures 4 and 5).