Two-photon microscopic imaging of small mesenteric arteries surrounded by PVAT showed that the number of cells positive for CD45/CD115 (monocytes and macrophages) and CD45/Gr-1 (neutrophils) tended to increase (P = 0.06) in the PVAT from just MetS mice (Figure 4B). The gene discussed is PTPRC; the disease is metabolic syndrome.