No significant difference in CBF at baseline (WT, 171.3 ± 9.5 vs CX3CR1-/-, 174.2 ± 10.1 ml/100 g/min, P > 0.05), ischemia (WT, 33.5 ± 14.3 vs CX3CR1-/-, 31.2 ± 13.1 ml/100 g/min, P > 0.05) and reperfusion (WT, 160.1 ± 15.1 vs CX3CR1-/-, 155 ± 12.3 ml/100 g/min, P > 0.05) was observed between WT and CX3CR1-/- mice. This evidence concerns the gene CX3CR1 and ischemia.