The clinical ER and HER2 status for 208 Han Chinese breast cancers were presented in Table 5; no basal-like breast tumors were ER positive, and most HER2-enriched breast tumors (around four-fifths) were clinically ER negative, whereas most of luminal-A and luminal-B subtypes were ER positive. The gene discussed is ESR1; the disease is breast carcinoma.