Causes of jaundice in malaria can be classified into direct causes, including malarial hepatitis and intravascular haemolysis of parasitized red blood cells as well as indirect causes including microangiopathic haemolysis associated with disseminated intravascular coagulation (DIC), G6PD-related haemolysis, antimalarial drug induction, septicemic hepatitis, and unrelated causes such as coexisting acute viral hepatitis [19, 20]. The gene discussed is G6PD; the disease is malaria.