Although some “in vitro” data implicating a Th2 activation is reported, as most other vasculitides, BD is mainly a Th1/Th17 type disorder with interleukin-2 (IL-2), IL-12, interferon-γ (IFN-γ), and IL-17 cytokine profile. The gene discussed is IFNG; the disease is Behcet disease.