As shown in Table 2 and Figure 3, circulating CXCL16 levels were negatively correlated with endogenous creatinine clearance rate (CCR), eGFR and blood albumin, and they positively correlated with creatinine, BUN, uric acid and 24 h proteinuria in DN subjects after adjustment for age, gender and BMI (p<0.05 respectively). Here, CXCL16 is linked to liver dysplastic nodule.