Figure 7A shows representative examples of NF-κB oligonucleotide binding from control and C26 extracts isolated at 23 days post-tumor cell inoculation. The specificity of protein-DNA binding was determined by addition of excess unlabeled consensus NF-κB oligonucleotide competitor to binding reaction. There was no significant difference in the amount of protein binding due to the tumor regardless of the number of days after tumor cell inoculation. Measurement of band intensity was combined for each time point and mean values were plotted for control vs. C26 mice (Figure 7B). The gene discussed is NFKB1; the disease is neoplasm.