PCBP1 and infection: At 8 h post-infection, ER-Tracker was also diffusely distributed in the cytoplasm (Fig. 5Ae), EV71 RNA was distributed in the cytoplasm (Fig. 5Af), but PCBP1 was mainly distributed in the cytoplasm (Fig 5Ag) and co-localized with both ER-Tracker and EV71 RNA (Fig 5Ah), perhaps in the ER-derived membrane, where the virus replication was occurred.