EGFR and central nervous system cancer: Several reports including ours suggest that human gliomas with high levels of PDGFRA expression are associated with frequent IDH1 mutation, deletion of chromosome 1p and 19q, G-CIMP or proneural phenotype, infrequent EGFR amplification, younger age at disease diagnosis and better survival compared to other gliomas with lower levels of PDGFRA expression, but high levels of EGFR expression [23]–[26].